Senior Scientist, Neuroimmunology, Biology-Discovery

Job Description

Position Summary

We are seeking a highly motivated, laboratory-based scientist to join the Neuroimmunology team at our Company. This role is ideal for a hands-on experimentalist with expertise in preclinical models, neuroimmunology, neurodegeneration, and translational biology. The successful candidate will independently design and execute in vitro and in vivo studies, generate mechanistic insights into microglial biology, and contribute to the discovery of novel therapies for CNS diseases.

Key Responsibilities

• Serve as a hands-on scientist conducting in vitro and in vivo procedures and downstream analyses.
• Play a key role in supporting pipeline programs by designing and executing studies, interpreting complex datasets, and communicating findings to cross-functional teams
• Generate and interpret pharmacology, efficacy, biomarker, and mechanistic datasets to support target validation and drug discovery programs.
• Perform CNS immune cell isolation, flow cytometry, immunophenotyping, molecular profiling, and histological analyses.
• Collaborate with multidisciplinary teams across pharmacology, immunology, chemistry, biologics, biomarker sciences, and data science.
• The individual is expected to provide strong scientific leadership, contribute to program strategy, and influence decision-making through data-driven recommendations

Required Qualifications

Education and experience:

• PhD in Neuroscience, Immunology, Cell Biology, Pharmacology, Bioengineering, Neurology, or a related STEM field; postdoctoral industry experience highly preferred.

OR

Master's degree Neuroscience, Immunology, Cell Biology, Pharmacology, Bioengineering, Neurology, or a related STEM field with:

• Minimum 8+years of pharmaceutical or biotechnology industry experience.

Required Skills:

• Extensive hands-on experience with rodent in vivo studies
• Experience with mouse models of neurodegeneration, neuroinflammation, or CNS disease.
• Expertise in flow cytometry, CNS immune cell isolation, immunohistochemistry, and molecular biology techniques.
• Proficiency with omics approaches (RNA-seq, single-cell technologies) and data analysis.
• Strong experimental design, statistical analysis, and problem-solving skills.
• Excellent communication and collaboration skills in a cross-functional research environment.

Preferred Qualifications

• Industry experience supporting discovery or early development programs in CNS disorders.
• Experience with Alzheimer's disease, Parkinson's disease, ALS, multiple sclerosis, or related neurodegenerative diseases.
• Hands-on experience with transgenic rodent models, including behavioral, pharmacology, and biomarker studies.
• Experience with primary microglia cultures, macrophages, immune cell assays, or iPSC-derived CNS cell systems.
• Familiarity with translational biomarkers, PK/PD relationships, and mechanism-based drug development.
• Experience working within multidisciplinary drug discovery teams and advancing programs from target validation through candidate selection.

• Prior experience leading collaborative projects, in particular, the ability to coordinate activities across multiple functions will be an important consideration

The ideal candidate is a highly independent scientist who enjoys working at the bench, excels in vivo experimentation, and is passionate about advancing innovative therapies for neurodegenerative diseases.

#EligibleforERP

Required Skills:

Assay Development, Cell Culture Techniques, Immunoassays, Immunology, In Vivo Models, Neurodegeneration, Neuroimmunology, Omics, Pharmacodynamics, Pharmacology

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

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We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

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