Associate Scientist, Upstream MSAT

Job title: Associate Scientist, Upstream MSAT

Location: Framingham, MA

About the Job

Sanofi’s Global MSAT (Manufacturing Sciences, Analytics, and Technology) acts as a crucial link between our R&D and Manufacturing entities, playing an instrumental role in enhancing our current portfolio and delivering future launches of high-quality and innovative drugs and vaccines. Global MSAT is a beacon of innovation and process excellence in Manufacturing, this includes guiding the journey of new products from their launch to commercial success, being at the forefront of Data Sciences and Digitalization. Join a team of talented and passionate international experts, scientists, and project leaders dedicated to inventing, designing, industrializing, and implementing cutting-edge industrial chemical and biological processes, analytical methods, and process modelling to successfully launch 3 to 5 new products by year.

The Associate Scientist position is part of the Upstream team in the Recombinant Drug Substance (DS) function within global MSAT and is based at the Mammalian Platform hub in Framingham, MA. The Recombinant DS function within global MSAT is the owner of Life Cycle Management (LCM) of DS processes. Implementation of second-generation processes is one of the top performance enablers for Sanofi’s biologics manufacturing network and integral to LCM. We deliver innovative, robust, and cost-effective next generation processes. In recent years we have successfully established second-generation manufacturing mammalian processes with a continuous process platform. The function is responsible for tech transfer, process validation, dossier preparation, & PAI support to enable launch of new and LCM products. We are pursuing future innovations such as digital labs, factory of the future, and advanced-analytics-based process understanding and control.

The successful candidate will work with a group of scientists and engineers responsible for development & characterization of next generation cell culture processes, technology transfer to a diverse network of manufacturing facilities, and support of advanced manufacturing investigations and process improvements for commercial products. We are looking for a candidate with excellent scientific and communication skills. This individual will work in a fast-paced, team environment, collaborating with colleagues across functions in the organization to solve a wide range of complex problems in creative and practical ways.

Join a global network that powers how Sanofi delivers — seamlessly, purposefully, and at scale. In Manufacturing & Supply, you’ll help reimagine how life-changing treatments reach people everywhere, faster.

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve lives.

Main Responsibilities:

• Work collaboratively within the Upstream group to execute and participate in the design of bench scale experiments

• Present data and results within department and project teams

• Author internal procedures and technical reports

• Contribute to project teams for technology transfer to pilot scale or commercial manufacturing

• Set-up and maintain upstream laboratory equipment, systems, and training

• Design and conduct experiments, interpret data, and present results to department and project teams

• Analyse process development and commercial manufacturing data in support of the MSAT mission; with the aim of improving process robustness, building process understanding and developing next-generation processes for monoclonal antibodies and recombinant proteins

• Contribute to technical investigations of complex deviations in manufacturing

• Contribute to establishment of best practices and technical ways of working within development and manufacturing teams

• Collaborate with other scientists/engineers across the biologics manufacturing network within Sanofi and with partnership organizations

About You

Basic Qualifications

• Bachelor's degree in chemical engineering, Biology, Biochemistry, or a similar or related field
• 0 to 5 years of hands-on experience in laboratory, pilot, or manufacturing scale for biologics products. Relevant academic experience (university projects, thesis work, or research) is valued and will be considered.

Preferred Qualifications

• Hands-on experience with cell culture, ideally in mammalian systems.
• Experience in one or more areas of upstream process development: process transfer, scale-up/scale-down, validation, or continuous process verification as applied to mammalian-expressed proteins.
• Experience with statistical analysis software.
• Strong scientific background, technical writing, and presentation skills.

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